Single Nucleotide Polymorphisms as Risk Variants in Crohn's Disease

ABSTRACT

Background: Crohn's disease is the most challenging, common type of autoimmune disorders due to which, intestine is inflamed but its causes have not been defined. Although Crohn's disease has been often thought of as an autoimmune disorder, it can be triggered by whatever that lead to the inflammation in the whole bowel. Henceforth, exploring trade-off among this disease and genomic variants supposedly will enhance the identification of important genes and in turn to the possible therapeutic protocols. The aim of the present study was to identify any association between Crohn's disease and single nucleotide polymorphisms.