Vitamin enriched diet on lipid metabolism in rats

ABSTRACT

Long term administration of diet enriched with vitamin A to experimental rats demonstrated a significant increase in liver total lipids, cholesterol, triglycerides and phospholipids. Similar findings [except for triglycerides] were observed in serum. Erythrocyte membrane phospholipids revealed an increase in only phosphatidylcholine. Results may be explained through a hypothesis of cholesterol with retinol and probable enhancement of liver lipid synthesis in response to long intake of vitamin A