Effect of combined general anesthesia and epidural ropivacaine with clonidine sufentanil versus sufentanil-clonidine on muscle relaxant requirement, hemodynamics and postoperative analgesia

ABSTRACT

Background: pain relief is a primary therapeutic objective in major abdominal surgery. Many strategies to control intraoperative and postoperative pain have been described. Epidural anesthesia is the most logical approach to produce effective analgesia, stable hemodynamics, and less anesthetic drugs use with more efficient muscle relaxation and less postoperative side effects. This study was designed to investigate the effect of epidural variables of drug combination on intraoperative hemodynamics and muscle relaxant drug needed during general anesthesia, also to evaluate postoperative analgesia, sedation and adverse effects of the given epidural drugs