three year study of the electrophoretic patterns of serum proteins with special reference to various globulinopathies in Saudis

ABSTRACT

Human sera comprising 545 specimens spread over a period of three years were analyzed electrophoretically for proteins. Only 159 samples [29%] exhibited abnormal serum protein patterns. They were in the order of inflammatory disorders [acute/chronic], 60 [37.7%], Polyclonal gammopathies,48 [30.1%], Cirrhosis, 22 [13.8%], Monoclonal gammopathies, 22 [13.8%], Agammaglobulinemia, 3 [1.9%], Nephrosis, 2 [1.2%], Protein-losing enteropathy, 1 [0.6%], Low-alpha 1 -antitrypsin, 1 [0.6%], Inflammatory diseases of various nature, therefore, constitute the major serum protein abnormalities in Riyadh. Moreover, their occurrence varies with age, sex and climatic conditions as elsewhere in the world