Relation between neutrophil function and the iron status in hemodialysis patients

ABSTRACT

Objectives: Neutrophil function in hemodialysis [HD] patients are altered by iron status and patients are suspected of having defectively regulated iron metabolism. Low serum ferritin reflects absolute iron deficiency whereas normal or high ferritin values in combination with low transferrin saturation [<20%] indicate functional iron deficiency. Therefore, the aim of the present study was to investigate functional and metabolic PMNL parameters of neutrophils isolated from three different groups of regular hemodialysis patients