Chronic exposure to MDMA [ecstasy] induces DNA damage, impairs functional antioxidant cellular defenses, enhances the lipid peroxidation process and alters testes histopathology in male rat

ABSTRACT

3,4-Methylenedioxymethamphetamine [MDMA or "ecstasy"] is consumed mainly by young population. For this reason, it is especially relevant to take into consideration the effects on the reproductive system. The influence of MDMA on the fertility and reproduction of the male rat was assessed in this study