Interaction effect of RsaI and BamHI polymorphisms of TGF-alpha, BMP2 and BMP4 on the occurrence of non-syndromic cleft lip and palate in Iranian patients
AJMB-Avicenna Journal of Medical Biotechnology. 2018; 10 (4): 248-252
in English
| IMEMR
| ID: emr-203113
ABSTRACT
Background:
Orofacial cleft is the most common congenital defect of the maxillofacial region. Its non-syndromic type is multi-factorial, and several genes are involved in its occurrence. This study aimed to assess the interaction effect of Rsal and BamHI polymorphisms of Transforming Growth Factor-alpha [TGFa] gene and Bone Morphogenetic Protein-2 [BMP2] and BMP4 variants on the occurrence of Non-Syndromic Cleft Lip and Palate [NSCLP] in the Iranian population
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Avicenna J. Med. Biotechnol.
Year:
2018
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