Genodermatoses in the gulf countries

ABSTRACT

Genodermatoses in the Gulf countries have been re- viewed. The high occurrence of diseases like epidermolysis bullosa, mal de Meleda and biotinidase deficiency have been noted. New syndromes are also continuously being reported. Molecular studies have revealed findings different from those described elsewhere. These have been linked to the large family size and tribal customs that lead to consanguinity. Influx of immigrants, wars and environmental pollutants are likely to worsen the situation. As treatment of genetic disorders is a challenging issue, prevention must be targeted by providing good premarital counseling and altering the tribal customs that promote consanguinity