Result of chemoradiotherapy in the treatment of laryngeal and hypopharyngeal carcinoma

ABSTRACT

Introduction: malignant tumors of head and neck [H and N] mostly squamous cell carcinoma [SCC] are common in Khorasan; the standard treatment consists of surgery with or without [pre or post operative] radiotherapy and occasionally only radical radiotherapy. According to many reports on high response rate of H and N metastatic tumorssometimes greater than 50% to the chemotherapeutic agents- it is accepted to use chemotherapy as a curative treatment modality in non-metastatic H and N tumors [1]. In our country there isn't any report about this treatment policy although there are many publications from European and American centers. In this paper we intend to present some parts of our experience on primary chemotherapy for nonrnetastatic SCC of laryngeal and hypopharyngeal carcinoma