[Evaluation of impaired glucose tolerance and type 2 diabetes mellitus prevalence in "PCOS" and necessity for screening in patients with "PCOS"]

ABSTRACT

Background: polycystic ovary syndrome [PCOS] which is characterized by menstrual irregularities [due to chronic anovulation] and hyperandrogenism is one of the most common endocrine disorders of women at reproductive age. The precise cause of PCOS is unknown, but it seems that several factors may have role in its pathogenesis. Insulin resistance and impaired insulin secretion are common findings in PCOS patients. Approximately 30 - 40 % of women with PCOS have impaired glucose tolerance or type 2 DM. According to my knowledge, there is no published study about prevalence of IGT and type 2 Diabetes Mellitus [type 2 DM] in Iranian women with PCOS. The aim of this prospective, controlled study was to determine the prevalence of abnormal glucose metabolism in women from North West part of the country