[Relationship between pancreas echogenisity and insulin sensitivity during the course of OGTT in children with beta-thalassemia major aged 10-20 years]

ABSTRACT

Background: increased echogenicity of pancreas, due to hemosiderosis, is a frequent finding in beta thalassemic paitents. Hemosiderosis also leads to beta - cell dysfunction. So diabetes and glucose intolerance are common consequences of hemosiderosis. The aim of this study was to investigate the association of increased pancreas. echogenicity [IPE] with insulin sensitivity in beta - thalassemic children aged 10-20 years