Comparative efficacy of topical fibrin sealants in a rat spleen trauma model

ABSTRACT

Objective: Management of splenic injury is a challenging surgical emergency. The spleen has important immunologic functions. Therefore, conservation of the spleen after trauma-whenever possible - is necessary. The present study was carried out to assess the efficacy of topical fibrin sealants [fibrin glue] in comparison with gelatin sponge [gelfoam] and oxidized regenerated cellulose [surgicel] in a rat spleen trauma model