Comparison of the efficacy of 06 months vs 09 months therapy in smear positive pulmonary TB

ABSTRACT

This study was aimed to assess and compare the efficacy of anti TB treatment for 6 months and 9 months duration. New cases of sputum smear positive TB were randomly allocated to one of the two groups. Both received RHZE [Myrin P] in first 2 months followed by RH for 4 months [Group A] and RH for 7 months [Group B]. Patients were followed at monthly interval for first 2 months and then 2 monthly intervals until completion of treatment and subsequently followed at 6 monthly intervals for 18 months to monitor for relapse. Sputum smears were examined for AFB at every visit and chest x-ray performed at 1, 2, 6 and 9 and then 6 monthly interval