Frequency of Beta Thalassemia trait among the healthy individuals: a single centre study
PAFMJ-Pakistan Armed Forces Medical Journal. 2018; 68 (6): 1716-1719
in En
| IMEMR
| ID: emr-206538
Responsible library:
EMRO
Objective: To determine the frequency of beta thalassemia trait among the asymptomatic healthy individuals
Study Design: Cross sectional study
Place and Duration of Study: This was carried out at Pakistan Air Force [PAF] Hospital Lahore from Jan 2016 to Jun 2017
Patients and Methods: The subjects were both male and female who came from all over Pakistan for central medical board for selection in Pakistan Air Force. Their ages were between 18 and 28 years. Their complete blood counts were measured on Sysmex KX 21 hematology analyzer. Candidates with microcytic hypochromic indices without anaemia were screened for beta thalassemia trait. Haemoglobin [Hb] electrophoresis was done on cellulose acetate paper at alkaline PH. HbA2 estimation was done by measuring the absorbance of elute on spectrophotometer. Beta thalassemia was diagnosed if the subject had HbA2 more than 3.5 percent. The data was analyzed using statistical package for social sciences [SPSS] software version 17
Results: A total of 2279 individual were enrolled in the study. Among them 2061 [90.4 percent] were males and 218 [9.6 percent] were females. Out of 2061 males, 91 [4.41 percent] were found to have beta thalassemia trait whereas among females only 6 [2.75 percent] out of 218 had beta thalassemia trait. The overall frequency of beta thalassemia trait was found to be 4.25 percent
Conclusion: The overall frequency of beta thalassemia trait in our study was found to be 4.25 percent. Thalassemia screening should be carried out along with normal health screening tests at least once in lifetime
Study Design: Cross sectional study
Place and Duration of Study: This was carried out at Pakistan Air Force [PAF] Hospital Lahore from Jan 2016 to Jun 2017
Patients and Methods: The subjects were both male and female who came from all over Pakistan for central medical board for selection in Pakistan Air Force. Their ages were between 18 and 28 years. Their complete blood counts were measured on Sysmex KX 21 hematology analyzer. Candidates with microcytic hypochromic indices without anaemia were screened for beta thalassemia trait. Haemoglobin [Hb] electrophoresis was done on cellulose acetate paper at alkaline PH. HbA2 estimation was done by measuring the absorbance of elute on spectrophotometer. Beta thalassemia was diagnosed if the subject had HbA2 more than 3.5 percent. The data was analyzed using statistical package for social sciences [SPSS] software version 17
Results: A total of 2279 individual were enrolled in the study. Among them 2061 [90.4 percent] were males and 218 [9.6 percent] were females. Out of 2061 males, 91 [4.41 percent] were found to have beta thalassemia trait whereas among females only 6 [2.75 percent] out of 218 had beta thalassemia trait. The overall frequency of beta thalassemia trait was found to be 4.25 percent
Conclusion: The overall frequency of beta thalassemia trait in our study was found to be 4.25 percent. Thalassemia screening should be carried out along with normal health screening tests at least once in lifetime
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Index:
IMEMR
Type of study:
Observational_studies
Language:
En
Journal:
Pak. Armed Forces Med. J.
Year:
2018