Histopathologic and immunohistopathologic evaluation of Pityriasis rosea

ABSTRACT

Biopsy specimens of secondary skin lesions of PR obtained from 20 patients were studied histopathologically and immunohistopathologically [using monoclonal antibodies directed against the dermal inflammatory infiltrate]. The tissue was paraffin embedded after fixation in BS and methanol 13 cases only gave positive results.Still the pattern of monoclonal expression in the stained cases varies. Our results suggest a possible role that may be mediated by the cellular immune reaction in the pathomechanism of such disease