Changes in the levels of some proteins in tears contact lens wearers

ABSTRACT

This study included 53 subjects; 18 controls not wearing contact lenses, 15 non-complicated daily soft lens wearers and 20 complicated daily lens wearers. The tear contents of some proteins were quantitated by immunodiffusion plates. A significant increase in IgA and IgG levels was found in the complicated wearer group compared with the control cases and the non-complicated group. Albumin levels were not statistically different between the three groups. Ceruloplasmin was significantly higher in the control group compared with the non- complicated group. However, no significant difference was found between the complicated and control groups. The difference was highly significant between the complicated and non-complicated groups. There was no significant correlation between IgG and IgA in all the three groups and a insignificant correlation between IgG, albumin and ceruloplasmin was found in the complicated cases