comparative study between the traditionally used drugs and the local application of honey in treatment of primary atrophic rhinitis [a clinical and histopathological study

ABSTRACT

Thirty patients with primary atrophic rhinitis were treated with alkaline nasal wash for [4] weeks and then with antibiotics according to culture and sensitivity for another [4] weeks. Then the patients were divided into equal three groups; the first group was treated by nasal drops used at E.N.T. department [Ain Shams University], the second group was treated with honey nasal drops and the third group was treated with honey packs for [8] weeks. Biopsy was taken from the inferior turbinate Mucosa before and after treatment. The results indicated that honey could improve the symptoms and signs of atrophic rhinitis in all the cases particularly in cases treated with honey packs, while there was improvement in 60% of cases treated by nasal drops used at E.N.T. department [Ain Shams University]. There was clinical improvement in 30% of cases treated with alkaline nasal wash and in 33.3% of cases treated by the combination of systemic antibiotics and alkaline nasal wash. There was a histological improvement with the use of honey and also with the use of nasal drops used at E.N.T. department [Ain Shams University]