effect of theophylline and bumetanide with spironolactone and ventilatory function in bilharzial patients with portal hypertension

ABSTRACT

Respiratory dysfunction in patients with hepatosplenic bilharziasis was recorded by many workers, some of them attributed this dysfunction to the increased size of the liver and spleen beside ascites; and others to the bilharzial pulmonary lesions whether vascular or parenchymal. The material of this work comprised 20 males with hepatosplenomegaly and pulmonary hypertension together with 10 normal control males, the pulmonary functions were done to all of them. Patients were treated with thiophylline and diuretics. It was noticed that some patients became significantly better after use of these drugs indicating that pulmonary dysfunction in these patients are mostly combined obstructive and restrictive