Effects of endogenous sex hormones on serum lipids, lipoproteins in women during reproductive age

ABSTRACT

Forty women of reproductive age were included in this study with aim of establishing the variation in serum lipids and lipoprotein are influenced by endogenous hormonal changes. Total cholesterol, triglycerides and phosholipids were determined in whole serum and in following lipoprotein fractions very low density lipoproteins [VLDL] low density lipoproteins [LDL] and high density lipoproteins [HDL] obtained by ultracentrifugation. A significant decrease was found in total cholesterol [P < 0.01] and phospholipids [P < 0.01] during the late luteal phase. The LDL cholesterol decrease during the luteal phase and VLDL cholesterol decrease during the luteal phase and VLDL cholesterol increased in early and mild luteal phases. The LDL phospho-lipids and VLDL triglycerides also showed a significant decrease during the luteal phase [P < 0.01]