place of the ultra sensible dosage of the TSH and the dosage of the free thyroxin in the supervise of primary hypothyroidism treated

ABSTRACT

Tyrotropin immunoradiometric assay [TSH-S] contribution evaluation is compared to free assay [T4L] during therapeutic control, on 79 patients with primary hypothyroidism under L-thyroxine both studied parameters in 34% of the cases. T4L and TSH-S proportions are observed respectively in 47 and 10 per cent of patients. Substutional treatment aims to plasmatic TSH equilibrium; its proportioning is essential and sufficient for the control of treated primary hypothyroidism; it enables to confirm clinical euthyroidism and to detect therapeutic deficiency or overproportioning