Total and fractionated serum lipids before, during and after the use of norgestrel

ABSTRACT

The effects of norgestrel on the fasting serum level of total lipids, B-lipoproteins, Cholesterol, phospholipids and triglycerides have been studied in 100 women. The total and fractionated serum lipids were estimated before, during and six months after discontinuation of the drug. There was a significant reduction of serum triglycerides and phospholipids. Total lipids and B-liopoproteins showed an insignificant increase, while cholesterol showed an insignificant decrease. As progestogens tended to improvement the hyperlipidaemic state, contraceptive pills containing progestogens would be the ideal choice for women with hyperelipaemia or with a family history of premature vascular accidents