Inhibition of protein-tyrosine kinase activity by Flavonoids of ononis sicula Guss
Alexandria Journal of Pharmaceutical Sciences. 1992; 6 (3): 283-285
in English
| IMEMR
| ID: emr-22905
ABSTRACT
The inhibitory activity of the protein-tyrosine kinase was tested on different extracts of Ononis sicula Guss. [Leguminosae]. Four known flavonoids; namely, pseudobaptigenin, eupatilin, jaceosidin and hispidulin, were isolated from the active 90% methanol extract. Hispidulin was found to be the most active with IC50-6 mu g/ml
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Pharmacology
/
Flavones
Language:
English
Journal:
Alex. J. Pharm. Sci.
Year:
1992
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