Sex hormones in men with myocardial infarction

The study included twenty male patients with acute myocardial infraction, and twenty matched normal subjects as controls. Serum levels of testosterone, estradiol [E2], progesterone, follicle stimulating hormone [FSH], Leutinizing hormone [LH]; and prolactin estimated in both patients and controls. The mean serum testosterone and estradiol were significantly decreased in patients compared with control group [P < 0.01 and P < 0.001 respectively]. Serum progesterone, follicle stimulating hormone and leutinizing hormone were significantly increased [P < 0.01,P < 0.001, and P < 0.05 respectively]. Mean serum prolactin level was not significantly different [P < 0.1]. Hence, we concluded that alterations in endogenous sex hormones are significantly associated with acute myocardial infarction