Epidemiological study of breast masses in relation to Histo-pathological profiles, El-Minya, Egypt

Breast lesions usually take the form of palpable masses, sometimes painful, more often not. The epidemiological study of cancer breast could give a clue to the possible risk factors. This case series study was done on 296 cases with breast lesions randomly chosen. Benign and malignant masses of the breast are virtually limited to the females. In benign masses, fibro-adenosis is the commonest type [44.2%] and duct papilloma is the least common one [4.6%]. Fibro- adenosis was common in unmarried and nulliparous women [17.5% and 16.6%, respectively], while women have more than four children have the lowest incidence [5.9%]. Fibro-adenosis was common in women taking no pills [18.4%]. Benign lesions was common in the 4th decade, the mean age was 33.5 +/- 8.3 years and painless swellings were common with relevant past and family history [X 2 + 65 and P <0.05]. The right breast was the commonest site [58.5%] and estrogen level was highly significantly increased in fibro-adenosis [P <0.001]. Uterine tumors were commonly associated with fibro-adenosis [11.3%]. In malignant masses, infiltrating duct carcinoma was the commonest [77.2%], it is common in unmarried and nulliparous women [15.2% and 24.1%, respectively]. There is no significant difference in women with malignant masses taken or not taken pills [X 2= 8.4 and P >0.05]. The mean age of malignant lesions was 44.5 +/- 8.7, painless swellings were common and right breast was the commonest site of masses [63.3%]. Estrogen level was highly significantly increased in infiltrating duct carcinoma [P <0.001]. Also, uterine tumors were commonly associated with infiltrating duct carcinoma [7.6%]