Cytogenetic prenatal diagnosis on 66 chorionic villus samples in Iran
Iranian Journal of Public Health. 1992; 21 (1-4): 51-60
in English
| IMEMR
| ID: emr-24064
ABSTRACT
A total number of 66 chorionic villus samples were cytogenetically investigated. The samples consisted of 30 experimental cvs from spontaneously aborted materialand 36 from live gestations.80% of the samples were successfully grown, of the 30 cases 40% [12] and 33% [10]contained a normal female and a normal male karyotype, respectively, 3.3% [1] and3.3% [1] had abnormal karyotypes [47,XX, + 21; 47, XY, + 18], respectively, and 16% [6] of the cultures did not grow of the 36 CVS, 80. 5% of the trophoblasts grew. 50% and 30.5% had normal karyotypes with 46, XY and 46, XX chromosome constitutions respectively, of those with a male karyotype, one case was revealed to have two mitoses with 47+Xy, +21 karyotype and was considered to be a Mosaic with a minor abnormal clone. One case [2.7%] was a twin; 5.5% of the samples did not grow and 11.1% of the villi were inadequate. No serious complications occurred after CVS. 12 girls and 9 biys were delivered at term and cytogenetic findings on the CVS were postnatally confirmed for normal cases and even for a Mosaic case
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Prenatal Diagnosis
/
Cytogenetics
Limits:
Humans
Language:
English
Journal:
Iran. J. Public Health
Year:
1992
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