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N-Glucosides: new phase II metabolites of two barbiturates
Medical Journal of the Islamic Republic of Iran. 1992; 6 (1): 63-66
in English | IMEMR | ID: emr-24844
ABSTRACT
The new phase-II N-glucoside metabolites of butobarbitone and pentobarbitone are identified and quantified in human urine after single doses of these drugs. The identification and quantification of these metabolites were carried out by mass spectroscopy technique [accurate mass measurement and high voltage scanning]. It was found that the butobarbitone N-glucoside comprised 26% of the dose with tl/2= 44h, while the pentobarbitone N-glucoside was 43% with t1/2= 40h
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Index: IMEMR (Eastern Mediterranean) Main subject: Barbiturates / Drug Design / Glucosides Language: English Journal: Med. J. Islamic Rep. Iran Year: 1992

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Index: IMEMR (Eastern Mediterranean) Main subject: Barbiturates / Drug Design / Glucosides Language: English Journal: Med. J. Islamic Rep. Iran Year: 1992