Inciolence of molder pregnancy in a University Hospital in Tehran: age and birth oroler

ABSTRACT

In a hospital-based study in Tehran from October, 1988, to October, 1989, the pathology findings of all D and Cs reported for abortion, hydatidiform mole, and blighted ovum are analyzed, and also the total number of term deliveries for this period are recorded. Overall incidence of hydatidiform mole in this study is 6.7/1000 live deliveries. First birth order at all age groups decreased the relative risk of hydatidiform mole which is statistically significant. The incidence of mole for first and second birth order at age group 15-19 is 0.4 and 10.6 per 1000 live births, respectively. At 20-24, the relative risk for hydatidiform mole is 2.13, which is statistically significant. The incidence of mole for this age group is 6.3/ 1000 live births for the first birth order and 23.8/1000 live births for 6th + birth order, which can mean that early and closely-spaced child bearing can be a contributory factor in this respect. Age 45 and over increases the risk of mole by 32 times. Since the risk of choriocarcinoma is increased after delivery of mole, recommendations are made for delay of child bearing for the young and against any pregnancies at older age