Systolic time intervals and 24-hours free urinary catecholamines in normo-and hypertensives

ABSTRACT

QS2 interval was significantly greater in patients with FEH than in both normotensives [P <0.001] and patients with BLH [P <0.01]. No significant difference was found between QS2 interval in patients with BLH and normotensives. There was an insignificant difference between LVET in the three groups investigated. PEP in patients with FEH was significantly greater than both normotensives [P <0.001] and patients with BLH [P <0.001], while PEP in patients with BLH was significantly shorter than in normotensives and in patients with FEH [P <0.001]. PEP/LVET in patients with FEH was significantly greater than in both normotensives and patients with BLH [P <0.001]. In patients with BLH, PEP/LVET was significantly less than in both normotensives and patients with FEH [P <0.001]. 24-hours urinary catecholamines in patients with FEH was significantly greater [P <0.01] than in normotensives but insignificantly different from that in patients with BLH. 24-hours urinary catecholamines in patients with BLH was significantly higher than in normotensives [P <0.001]. The present study showed that myocardial contractility is diminished in patients with fixed essential hypertension, and increased in patients with border line hypertension than in the control subjects. Also, the study proved that the overall activity of the sympathoadrenal systems is increased in patients with both fixed essential and border line hypertension than in the control subjects: