Effect of exchange transfusion on serum toxicity: relation to complications

ABSTRACT

Our work included 27 cases underwent exchange transfusion, 15 with hyperbilirubinemia, 7 neonatal sepsis, 3 D.I.C and 2 cases with RDS. We found increased serum sodium and serum tonicity in all cases underwent E.T. This increase in tonicity wag higher in infants in which E.T was done early in the first 3 days of life [serum tonicity wag 19.95 mosm/L], in infants with small gestational age [Serum tonicity was 32.57 mosm/L in neonates between 27-28 weeks and 28.02 in neonates between 29-30 weeks] and in infants with low birth weight [Serum tonicity was 20.27 mosm/L in cases < 1000 gm]. The complications which occurred during E.T includes Seizures in 7 cases; apnea in 6 cases; bradycardia < 80/m in 5 cases; shock like appearance in 4 cases. The mortality wag 5 cases[18.8 percent] and all contracted hypertonicity