Effect of Nigella sativa extract on experimental giardiasis

ABSTRACT

Antiprotozoal effect of alcoholic extract of Nigella sativa seeds was studied in experimental giardiasis in comparison with metronidazole drug. A single oral dose of Nigella sativa seeds alcoholic extract [40 mg/kg body weight] was found to be as effective as a single oral dose of metronidazole [40 mg/kg body weight] as both gave a cure rate of 80%. In addition, Nigella sativa seeds extract showed some protective action against further infection with giardiasis in experimental animals, while metronidazole did not