Comparative enzymatic studies on 5-azacytidine pre-treated Biomphalaria Alexandrina snails

ABSTRACT

Biochemical elucidation of the mode of action of 5-azacytidine on Biomphalaria alexandrina snails, the specific intermediate hosts for Schistosoma mansoni was carried out. The effect of 5-azacytidine on the enzymatic activity of Lactate dehydrogenase [LD], Glucose-6 phosphate dehydrogenase [G - 6 - pd] and on the glutathione content in the haemolymph of the snails is reported