Serum procollagen III amino-terminal peptide [P III NP]: a non-invasive procedure for assessment of liver fibrosis

ABSTRACT

Serum pro-collagen III and liver function tests were estimated in 20 healthy subjects and 71 patients with chronic liver disease in a trial to find out its correlation with clinical, laboratory and histological parameters as well as its diagnostic value. From the results obtained, it was concluded that serum P III NP may be a good marker of liver fibrosis and may be used in differentiating fibrotic liver diseases from those with no or minimal fibrosis and may be a good prognostic clinical marker in the assessment of clinical severity of the disease