Impact of vulval warts on uterine cervix-new colposcopic finding

ABSTRACT

There is a growing interest in human papilloma virus [HPV] infection of the cervix. The aim of, this work, is to study the impact of vulval warts on HPV related cervical disease and to compare, the results with findings in women without vulva warts. Seventy women paticipated in this work 30 cases with vulval warts [study group] and 40 cases withhout vulval warts [control group]. All cases were subjected for full medical history, cervicovaginal cytology, colposcopy and biopsy from colposcopically abnormal areas. Cytological examination revealed 7 cases with cervical HPV infection [23.3%] in the study group, compared to 2 cases in the control group [5%] [P<0.01]. Three study cases showed dyskaryosis [2 mild and one moderate]. Abnormal colposcopic findings were detected in 13 cases of the study group [43.2%], compared to 3 cases [7.5%] of the control group [P<0.01]. The finding of micropapillary aceto - white epithelium with partial iodine uptake was prominently associated with cervical HPV infection in cases of vulval warts. Histopathology of the colposcopically directed biopsies revealed 5 cases with HPV infection [Flat condyloma in 2 cases and flat condyloma with CINI in 3 cases] and 2 cases with CIN, [one CINI I and one CIN II] in the study group, compared to only one cases of flat condyloma in the control group. The importance of these findings are discussed