Prophylactic antibiotic in Caesarean section

This study was conducted to compare the effect of perioperative prophylactic antibiotics versus routine post-operative antibiotics an the post-operative febrile morbidity in cases undergoing caesarean section [C.S], Ninety cases given prophylactic antibiotics [45 cases given Ampicilln and 45 cases given lincomycin] and 100 cases were studied retrospectively who had received post-operative antibiotics. Wound infection encountered in 6.7% in those received prophylactic antibiotics and in 10% of the retrospective control. Staph. aureus, proteus mirabilis, Pseudomonas aerugenosa and Klebsiella sp. are the organisms isolated from the infected wounds in those received prophylactic antibiotics. Febrile morbidity occurred in 14.4% in those antibiotic and in 25% of the post-operative antibiotic group. Significant bacteriuria detected in 45.6% of the studied cases before treatment. In the present study 64.4% of the studied cases showed positive intraoperative isolates from tower segment of uterus before treatment. Staph-epidermidis represent 44% of the isolated organisms, staph. aureus represent 10.7% of the isolated organism, while Strept. faecalis, diphteroides and Klebsiella sp. represent 9.3% of the isolated organisms. The hospital cost of non-morbid cases in the prophylactic antibiotic group was markedly less than in those who received post-operaive treatment