Condensed pyrimidines XV

ABSTRACT

The ring systems pyrrolo [1,2-c] pyrimidine and pyrimido [1,6-a] azepine [I] were subjected to acylation giving rise to a tricyclic nuclei, pyrimido [5,4-e] pyrrolo [1,2-c] pyrimidine and pyrimido [4',5' 4,5] pyrimido [1,6-a] azepine [II]. These compounds were reacted with different amines to give the corresponding 3-alkylaminopropyl derivatives [IV]. The tetracycles pyrrolo [1,2-a] pyrrolo [1',2' 1,6] pyrimido [4',5'-a] pyrimidine and pyrrolo [1",2" 1',2'] pyrimido [4',5' 4,5] pyrimido [1,6-a] azepine [V] were prepared through different routes