Light and electron microscopic observation on rat molar periodontal ligament after intraperitoneal injection of vinblastine
EDJ-Egyptian Dental Journal. 1993; 39 (3): 495-500
in English
| IMEMR
| ID: emr-27619
ABSTRACT
The effect of intraperitoneal injection of Vinblastine sulfate on rat periodontal ligament was studied. Cells still synthetize collagen after 2 hours of the injection with evidence of loss of extracellular collagen fibers orientation. Tubular lysosome could not be detected after 2 hours with formation of lysosomal clusters in the cell center. After 4 hours of administration, evidences of cell degeneration were observed. The present study has shown that Vinblastine produces effect on fibroblasts as early as two hours after injection
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Rats
/
Vinblastine
/
Microscopy, Electron
/
Injections, Intraperitoneal
/
Microscopy
/
Molar
Limits:
Animals
Language:
English
Journal:
Egypt. Dent. J.
Year:
1993
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