Journal of the Egyptian Society of Parasitology. 1993; 23 (3): 877-86
in English
| IMEMR
| ID: emr-28435
ABSTRACT
The effect of single dose of praziquantel [400 mg/kg] or two doses on two consecutive days was studied in mice infected with S. mansoni. With the single dose there was improvement in the serum protein pattern, towards pre-infection values and a transient rise in serum transminases which soon declined to normal Improvement was more evident after using two doses of praziquantel [P < 0.001]. Worms were eradicated by 70%, 77% and 80% after the single dose and by 88%, 92% and 95% after two doses. Granuloma size was reduced by 50%, 54% and 60% after single dose and by 58% and 73% respectively after 10, 20, and 30 days from treatment
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Praziquantel
/
Schistosomiasis mansoni
/
Infections
/
Liver
/
Liver Function Tests
Language:
English
Journal:
J. Egypt. Soc. Parasitol.
Year:
1993
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