Cyclosporin A in Behcet's uveitis

ABSTRACT

Six patients [4 males, 2 females] with confirmed diagnosis of Behcet's disease and uveitis were put on Cyclosporin A [CyA], a potent cell mediated immune suppressant. A total of Eleven eyes were studied, with significant improvement [P< 0.01]. There was also improvement in the extraocular manifestations of the disease. Though the drug seems to be a good substitute to steroids, chlorumbucil and colchicine, a double-blind controlled trial to compare [CyA] with these drugs needs to be done in the future