Immunoglobulin level and the value of IFAT test in the diagnosis of cutaneous leishmaniasis

ABSTRACT

A group of 58 patients complaining from cutaneous leishmaniasis attended the Dermatology Department of the College of Medicine of Baghdad University were studied through a period from Nov. 1988 -, June, 1989 to detect the level of immunolglobulins and to interpret the value of immuno flourescent antibody test [IFA] in the diagnosis of cutancous leishmaniasis. No significant changes in the level of immunoglobulins were found. Concerning the IFA test, it was found that it was one of the good laboratory methods; which may help the diagnosis of -cutaneous leishmaniasis. Its high positivity was especially related to the number of the lesions of cutaneous leishmaniasis [in 3-6 lesions the positivity was up to 81.8%] and the duration of the infection [in 3-5 months of duration 87.5% positive]. This started to decline after 5 months. Comparing the results of IFA lest to that of stained smear and cultures. It was found that IFA test showed the highest positivity [68.2%, 48%, 48% respectively]