Cardiac performance in typhoid fever

ABSTRACT

The cardiac performance was studied in 19 patients with typhoid fever within 10 days from the onset of fever, 15 of them were restudied in the convalescent period [4 weeks] together with 8 feverish subjects with common cold as controls. There were ECG changes in 46% of cases in the form of prolongation of the P-R interval, Q-Tc interval, S-T and T wave changes. In echo doppler study there was no significant changes in left ventricular systolic function. There was significant change in left ventricular diastolic function during the acute phase of the disease in the form of decrease in velocity of E relative to A and reversal of E/A ratio. The results conclude that the echo doppler change had a direct relation to the clinical severity of the disease and was corrected during the convalescent period of typhoid fever