Role of prolactin metabolism in bilharzial hepatic fibrosis associated with sexual disturbances

ABSTRACT

Serum prolactin levels were assayed in 20 male patients with bilharzial liver fibrosis Also, LH and FSH were measured. Twelve male individuals with no known diseases which affect pituitary hormones constituted the control group Cases with hyperprolactinaemia [>20mg/ml] and associated with sexual disturbances [18 patients] were treated with bromocriptine [2.5mg tds for one month]. After treatment, serum prolactin levels were reassayed with revaluation of sexual disturbances. The treated cases showed improvement of the reproductive state in the form of increased libido and improved potency.This could be attributed to the significant decrease of serum prolactin levels to within reference ranges