Evaluation of the role of prophylactic antibiotics in the management of simple accidental wounds

ABSTRACT

Four hundred and forty seven patients were randomized into two groups. One group of patients were given prophylactic antibiotics in conjunction with wound closure and the other group were sutured without antibiotic, then the wounds were evaluated for occurrence of infection. Prophylactic antibiotics failed to produce any significant improvement concerning wound infection in any of the subgroups of those patients receiving antibiotics