Gastric metaplasia of duodenal mucosa and Helicobacter pylori organism in duodenal ulcer patients

ABSTRACT

Endoscopic biopsies from gastric antrum and duodental bulb were taken from 30 chronic active doudenal ulcer patients to evaluate the association between gastric metaplasia and degree of duodenal and antral inflammation and the presence of H. pylori organism in gastric and duodenal biopsies. Duodenal and antral gastritis was present in all cases [100%]. Gastric metaplasia was found in 80% of duodenal biopsies. H. pyllori organism was found in 90%, 80% of antral and duodenal biopsies, respectively. This study indicated that H. pylori organism and gastric metaplasia can be a factor in pathogenesis of duodenitis and duodenal ulceration