Maternal inspired oxygen fraction [F1O2] 0.5 and 1.0 with isoflurane for cesarean section

ABSTRACT

Thirty mothers ASA1 or 2 undergoing general anesthesia for elective cesarean section not for fetal distress indication, were allocated randomly to receive either FIO 2 0.5 [group 1] or FIO 2 1.0 [group 2] during isoflurane anesthesia 1-1.5 MAC. The mean umbilical venous PO2 was greater in the second group. Babies born to mothers in this group required less resuscitation than those in the first group, and there was a tendency to higher Apgar scores at 1 minute in group 2, though this was not statistically significant. There was no increase in the incidence of awareness in group 2. These results support other studies stating that the use of 100% oxygen can significantly improve fetal oxygenation during cesarean section