Antenatal significance of glycosylated hemoglobin [HbA1c] in high risk pregnancy

ABSTRACT

The present study was carried out to evaluate the antenatal significance of carbohydrate intolerance in high risk pregnancy in chosen groups from each trimester with estimation of glycosylated haemoglobin value in Pakistani women. Glycosylated Haemoglobin [HbA[1C]] was assayed during different trimesters of pregnancy in 54 women. Twenty four pregnant women acting as controls, were compared with 30 women having high risk pregnancy. Three of the women belonging to the high risk group turned out to be diabetics and were excluded from the study. The results between different trimesters of control group and high risk pregnancy group were found statistically significant. Furthermore, significant differences were found within trimesters of high risk pregnancy. It is suggested that HbA[1C] is useful in addition to conventional oral glucose tolerance test as a screening tool for gestational diabetes