Successful use of 1-alpha calcidiol in the treatment of generalized pustular psoriasis with hypocalcemia

ABSTRACT

Since the original description of generalized pustular psoriasis by Von Zumbusch, there have been different hypotheses regarding its pathogenesis. Hypocalcaemia is a known interesting manifestation which sometimes appears to be secondary to this condition and on other occasions a known precipitant. We report a patient who developed generalized pustular psoriasis associated with hypocalcaemia with a favourable response to 1-alpha calcidol therapy