levels of lipoprotein in male and female Sudanese diabetics

ABSTRACT

In view of the high incidence of coronary heart disease in diabetic women, lipid and lipoprotein values, including fasting triacylgycerol [TG], total cholesterol [TC] and its major fractions were obtained from 18 men and 30 women with insulin dependent diabetes mellitus [IDDM] and 22 men and 68 women with non insulin dependent diabetes mellitus [NIDDM], at Khartoum Teaching Hospital. 20 healthy men and 30 health females were chosen as control. Male diabetics showed significantly high levels of very low density lipoprotein - cholesterol [VLDL - C] compared to their sex matched controls, while female diabetics showed high total cholesterol and low density lipoprotein - cholesterol [LDL - C] compared to their controls. NIDDM diabetics showed significant triacylgycerol level and low HDL - C level than sex matched controls [P < 0.05, P < 0.001 respectively]. Considering all the obtained values from different parameters, we conclude that male diabetics were less liable to develop coronary heart disease than female diabetics who might be subjected to an increasingly risk to develop coronary disease