Les caracteristiques hematologiques des syndromes myelodysplasiques lors de la premiere presentation: etude retrospective de 14 cas
Tunisie Medicale [La]. 1993; 71 (6-7): 333-8
in French
| IMEMR
| ID: emr-31231
ABSTRACT
The haematological characteristics of 14 cases of primary mylodysplastic syndromes [MDS] were reviewed at initial presentation on the bases of FAB classification. The distribution according to the 5 types of MDS is AR = 3 patients, ASAI = 3 patients, AREB = 4 patients, AREB-T-3 patients and LMMC = 1 patient. Two third of the patients are over 60 years. The anemia is present at all of patients, while the leukopenia and the thrombopenia are noted respectively in 28.4% and 53.8% of cases. The pancytopnia is noted in 28.4% of cases. The cytologic and histologic study of the bone marrow constitute they key of diagnosis. The bone marrow is normocellular or hyper- cellular in all of cases. The dyserythropoiesis is marked in the cases of AR and ASAI with Perls coloration strongly positive in the last [52% of total erythroblast]. In the other hand, the dysgranulopoiesis is important in the cases of AREB, AREB-T and LMMC, with expressive medullar blastosis [10% to 20%]
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Preleukemia
/
Anemia, Refractory, with Excess of Blasts
/
Hematology
Limits:
Humans
Language:
French
Journal:
Tunisie Med.
Year:
1993
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