Effects of oestradial administration on hepatorenal functions in male rats

ABSTRACT

Twenty-five mature male albino rats were used in the present study to clarify the effects of estradiol on hepatorenal function. They were divided into two groups [control group and treated group]. The results showed that there was an increase in serum level of alkaline phosphatase, ALT, AST, bilirubin, urea, creatinine, triglycerides and cholesterol following estradiol treatment. So, it was concluded that, administration of estradiol at high dose rates to mature male rats has a serious harmful effect on hepatorenal function