Preliminary study on formulation and application of aflatoxins-antidote

ABSTRACT

Chemical assay showed that the concentration of aflatoxin B1 was proved to be 250 ug/kg finisher feed. To testify the validity of this appropriate aflatoxins-antidote, 200 Lohman broilers aged 4 weeks and weighing approximately 1065 g each, were obtained and randomly distributed into equal four groups. Two groups only received single oral capsule daily for 30 successive days, meanwhile, they were fed on aflatoxin B1 contaminated ration containing 250 and 125 ug/kg feed for the high and low level treated groups, respectively. The other two groups were identified as positive and negative control groups. The negative group fed on a ration of 250 ug aflatoxin B1/kg, both control groups received no aflatoxins-antidote. Data showed that the performance of both treated groups showed an obvious resistance to aflatoxin B1-contamination. The average total body gain of both high and low level treated groups were 93.8 and 104.8% relative to the negative control group, while the corresponding figure obtained from the positive control group reduced up to 25.9% after 30 successive days of feeding on aflatoxin B1 contaminated ration. Similarly, the percentages of average feed conversion of both high and low level treated groups showed 104.3% and 94% relative to negative control, while the corresponding figure obtained from positive control was 353%. In other words, consuming 2244 and 2262 g aflatoxin B1 contaminated ration resulted in body weight gain of 800 and 894 g in the two treated groups, which received daily capsules of aflatoxins- antidote, while the average body weight gained from positive control consuming 2106 g was 221 g after the same period